IGKV1OR2-2

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, IGKV1OR2-2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,583 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible IGKV1OR2-2-associated GO terms across cancer lineages are B cell mediated immunity, Immunoglobulin production, and Antibacterial humoral response. Each is linked with IGKV1OR2-2 in more than 23 cancer types. Because this analysis shows association rather than direction, both IGKV1OR2-2-to-partner and partner-to-IGKV1OR2-2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGKV1OR2-2→partner) and Y-score (partner→IGKV1OR2-2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
THCAB cell mediated immunity →+0.108+0.214<.001<.001324
ESCAImmunoglobulin production →+0.082+0.140<.001<.001323
SARCAntibacterial humoral response →+0.173+0.065<.001<.001323
SARCAntigen receptor-mediated signaling pathway →+0.069+0.103<.001<.001322
ESCARegulation of B cell activation →+0.051+0.169<.001<.001322
SARCPositive regulation of leukocyte proliferation →+0.060+0.060<.001.001322
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,583 associations by consensus.

Exploration