IGKV1OR2-118

Across TCGA patient cohorts, IGKV1OR2-118 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,848 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible IGKV1OR2-118-associated GO terms across cancer lineages are B cell mediated immunity, Antibacterial humoral response, and Immunoglobulin production. Each is linked with IGKV1OR2-118 in more than 25 cancer types. Because this analysis shows association rather than direction, both IGKV1OR2-118-to-partner and partner-to-IGKV1OR2-118 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, B cell mediated immunity grouped by IGKV1OR2-118-low versus IGKV1OR2-118-high in THCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGKV1OR2-118→partner) and Y-score (partner→IGKV1OR2-118) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THCA	B cell mediated immunity →	+0.100	+0.572	<.001	<.001	3	26
THCA	Antibacterial humoral response →	+0.172	+0.540	<.001	<.001	3	26
STAD	Immunoglobulin production →	+0.103	+0.946	<.001	<.001	3	26
THCA	Complement activation, classical pathway →	+0.189	+0.511	<.001	<.001	3	25
THCA	Antimicrobial humoral response →	+0.115	+0.543	<.001	<.001	3	25
CHOL	Interleukin-6 production →	+0.043	+0.512	<.001	<.001	3	25

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,848 associations by consensus.

B cell mediated immunity by IGKV1OR2-118 expression — THCA

Explore this box plot interactively →