IGKV1OR2-108

Across TCGA patient cohorts, IGKV1OR2-108 protein abundance is significantly associated with the RNA expression of many other genes, with 9,155 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IGKV1OR2-108-associated genes across cancer lineages are FANCE, FCRL5, and IGHV3-21. Each is linked with IGKV1OR2-108 in more than 4 cancer types. Because this analysis shows association rather than direction, both IGKV1OR2-108-to-partner and partner-to-IGKV1OR2-108 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IGKV1OR2-108 versus FANCE in BRCA, with a Pearson correlation of -0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGKV1OR2-108→partner) and Y-score (partner→IGKV1OR2-108) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	FANCE →	-0.935	-0.575	.003	.009	3	5
LSCC	FCRL5 →	+1.222	+1.000	<.001	<.001	3	4
LSCC	IGHV3-21 →	+1.127	+0.858	<.001	<.001	3	4
GBM	IGKV3-20 →	+1.455	+0.433	.003	.002	3	4
LSCC	XPO5 →	-0.598	-0.569	<.001	.003	3	4
OV	IGKJ4 →	+3.411	+0.901	.002	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,155 associations by consensus.

IGKV1OR2-108 vs FANCE — BRCA

Explore this scatter interactively →