IGKV1OR10-1

Across TCGA patient cohorts, IGKV1OR10-1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,866 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible IGKV1OR10-1-associated GO terms across cancer lineages are Complement activation, classical pathway, B cell mediated immunity, and Antimicrobial humoral response. Each is linked with IGKV1OR10-1 in more than 27 cancer types. Because this analysis shows association rather than direction, both IGKV1OR10-1-to-partner and partner-to-IGKV1OR10-1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Complement activation, classical pathway grouped by IGKV1OR10-1-low versus IGKV1OR10-1-high in THCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGKV1OR10-1→partner) and Y-score (partner→IGKV1OR10-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THCA	Complement activation, classical pathway →	+0.195	+0.818	<.001	<.001	3	27
ESCA	B cell mediated immunity →	+0.096	+0.612	<.001	<.001	3	27
THCA	Antimicrobial humoral response →	+0.111	+0.870	<.001	<.001	3	27
THCA	Antibacterial humoral response →	+0.170	+0.894	<.001	<.001	3	27
THCA	Humoral immune response mediated by circulating immunoglobulin →	+0.160	+0.804	<.001	<.001	3	27
TGCT	Antigen receptor-mediated signaling pathway →	+0.068	+0.555	<.001	<.001	3	26

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,866 associations by consensus.

Complement activation, classical pathway by IGKV1OR10-1 expression — THCA

Explore this box plot interactively →