IGKV1D-33

Across TCGA patient cohorts, IGKV1D-33 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,853 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible IGKV1D-33-associated GO terms across cancer lineages are Antibacterial humoral response, B cell mediated immunity, and Antimicrobial humoral response. Each is linked with IGKV1D-33 in more than 28 cancer types. Because this analysis shows association rather than direction, both IGKV1D-33-to-partner and partner-to-IGKV1D-33 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Antibacterial humoral response grouped by IGKV1D-33-low versus IGKV1D-33-high in THCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGKV1D-33→partner) and Y-score (partner→IGKV1D-33) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THCA	Antibacterial humoral response →	+0.168	+0.821	<.001	<.001	3	28
CHOL	B cell mediated immunity →	+0.106	+1.922	<.001	.002	1	29
THCA	Antimicrobial humoral response →	+0.110	+0.802	<.001	<.001	3	27
THCA	Humoral immune response mediated by circulating immunoglobulin →	+0.157	+0.753	<.001	<.001	3	27
CHOL	Cytokine production involved in immune response →	+0.040	+1.671	<.001	.004	2	27
THCA	Negative regulation of T cell mediated immunity →	+0.068	+0.712	<.001	<.001	3	26

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,853 associations by consensus.

Antibacterial humoral response by IGKV1D-33 expression — THCA

Explore this box plot interactively →