IGKV1D-32

Across TCGA patient cohorts, IGKV1D-32 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,141 significant associations in total. STAD shows the largest number of these associations.

The most reproducible IGKV1D-32-associated GO terms across cancer lineages are Antigen receptor-mediated signaling pathway, B cell mediated immunity, and B cell activation. Each is linked with IGKV1D-32 in more than 21 cancer types. Because this analysis shows association rather than direction, both IGKV1D-32-to-partner and partner-to-IGKV1D-32 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Antigen receptor-mediated signaling pathway grouped by IGKV1D-32-low versus IGKV1D-32-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGKV1D-32→partner) and Y-score (partner→IGKV1D-32) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Antigen receptor-mediated signaling pathway →	+0.090	+0.089	<.001	<.001	3	21
SARC	B cell mediated immunity →	+0.109	+0.031	<.001	.005	2	22
ESCA	B cell activation →	+0.082	+0.098	<.001	<.001	3	21
ESCA	Lymphocyte migration →	+0.082	+0.085	<.001	<.001	3	20
ESCA	Regulation of leukocyte proliferation →	+0.081	+0.140	<.001	<.001	3	20
ESCA	Positive regulation of leukocyte proliferation →	+0.084	+0.077	<.001	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,141 associations by consensus.

Antigen receptor-mediated signaling pathway by IGKV1D-32 expression — ESCA

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