IGKV1D-32

Across TCGA pan-cancer cohorts, IGKV1D-32 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of IGKV1D-32’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where IGKV1D-32 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types IGKV1D-32 is over-expressed in tumor, although a few such as COAD and BRCA show the opposite, repressed pattern.

LUAD, COAD, and BRCA are the cancer types where IGKV1D-32 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in IGKV1D-32 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	All	All	+0.251	<.001	4	view →
COAD	All	All	−0.165	.001	4	view →
BRCA	Female	II,III,IV	−0.043	.008	4	view →
READ	All	All	−0.247	.034	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

IGKV1D-32–LUAD

Open the LUAD breakdown →