IGKV1D-13

Across TCGA patient cohorts, IGKV1D-13 RNA expression is significantly associated with the mutation status of many other genes, with 7,624 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IGKV1D-13-associated genes across cancer lineages are TP53, TTN, and XIRP2. Each is linked with IGKV1D-13 in more than 2 cancer types. Because this analysis shows association rather than direction, both IGKV1D-13-to-partner and partner-to-IGKV1D-13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TP53 grouped by IGKV1D-13-low versus IGKV1D-13-high in READ.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGKV1D-13→partner) and Y-score (partner→IGKV1D-13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	TP53 →	-0.890	-0.729	.003	.008	3	3
LUSC	TTN →	-0.375	-1.016	<.001	<.001	3	3
LUSC	XIRP2 →	-0.943	-0.624	.002	.007	3	3
UCEC	B3GNT5 →	+1.990	+0.847	.002	.007	3	3
BRCA	UTRN →	+3.700	+1.561	.001	<.001	3	2
STAD	FLNC →	-3.459	-1.291	.005	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,624 associations by consensus.

TP53 by IGKV1D-13 expression — READ

Explore this box plot interactively →