IGKV1D-13

Across TCGA patient cohorts, IGKV1D-13 protein abundance is significantly associated with the RNA expression of many other genes, with 2,447 significant associations in total. GBM shows the largest number of these associations.

The most reproducible IGKV1D-13-associated genes across cancer lineages are GKN2, IGKV1-13, and CREG1. Each is linked with IGKV1D-13 in more than 2 cancer types. Because this analysis shows association rather than direction, both IGKV1D-13-to-partner and partner-to-IGKV1D-13 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IGKV1D-13 versus GKN2 in LSCC, with a Pearson correlation of 0.22.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGKV1D-13→partner) and Y-score (partner→IGKV1D-13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	GKN2 →	+0.645	+0.585	.007	.002	3	3
BRCA	IGKV1-13 →	+1.142	+0.862	.003	<.001	3	3
GBM	CREG1 →	+0.614	+0.421	.003	.009	3	2
CCRCC	HSPD1P11 →	+0.677	+0.538	.002	.006	3	2
GBM	HAMP →	+0.817	+0.373	.005	.001	3	2
UCEC	IRAG2 →	+0.538	+0.544	.008	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,447 associations by consensus.

IGKV1D-13 vs GKN2 — LSCC

Explore this scatter interactively →