IGKV1D-13

Across TCGA patient cohorts, IGKV1D-13 protein abundance is significantly associated with the protein abundance of many other proteins, with 10,117 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible IGKV1D-13-associated proteins across cancer lineages are IGHV4-28, IGKV1-16, and IGKV3-7. Each is linked with IGKV1D-13 in more than 5 cancer types. Because this analysis shows association rather than direction, both IGKV1D-13-to-partner and partner-to-IGKV1D-13 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IGKV1D-13 versus IGHV4-28 in COAD, with a Pearson correlation of 0.55.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IGKV1D-13→partner) and Y-score (partner→IGKV1D-13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	IGHV4-28 →	+1.083	+1.301	<.001	.003	2	6
LUAD	IGKV1-16 →	+0.720	+0.784	<.001	<.001	3	5
GBM	IGKV3-7 →	+0.548	+0.492	<.001	<.001	3	5
BRCA	IGHV5-51 →	+0.672	+0.909	<.001	<.001	3	4
BRCA	IGKV1-27 →	+0.705	+0.748	<.001	<.001	2	5
BRCA	IGKV3D-20 →	+0.964	+0.814	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,117 associations by consensus.

IGKV1D-13 vs IGHV4-28 — COAD

Explore this scatter interactively →