IGKV1D-12

Across TCGA patient cohorts, IGKV1D-12 mutation is significantly associated with the immune_cell of many other genes, with 1 significant associations in total. LUSC shows the largest number of these associations.

The most reproducible IGKV1D-12-associated genes across cancer lineages are Neutrophils. Each is linked with IGKV1D-12 in more than 1 cancer types. Because this analysis shows association rather than direction, both IGKV1D-12-to-partner and partner-to-IGKV1D-12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Neutrophils grouped by IGKV1D-12-low versus IGKV1D-12-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGKV1D-12→partner) and Y-score (partner→IGKV1D-12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	Neutrophils →	+0.018	+3.469	<.001	.031	3	1

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

Neutrophils by IGKV1D-12 expression — LUSC

Explore this box plot interactively →