IGHVIII-76-1

Across TCGA patient cohorts, IGHVIII-76-1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,693 significant associations in total. STAD shows the largest number of these associations.

The most reproducible IGHVIII-76-1-associated GO terms across cancer lineages are Vesicle coating, Regulation of protein exit from endoplasmic reticulum, and Protein exit from endoplasmic reticulum. Each is linked with IGHVIII-76-1 in more than 15 cancer types. Because this analysis shows association rather than direction, both IGHVIII-76-1-to-partner and partner-to-IGHVIII-76-1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vesicle coating grouped by IGHVIII-76-1-low versus IGHVIII-76-1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHVIII-76-1→partner) and Y-score (partner→IGHVIII-76-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Vesicle coating →	+0.048	+0.123	<.001	<.001	3	16
STAD	Regulation of protein exit from endoplasmic reticulum →	+0.058	+0.139	<.001	<.001	3	16
STAD	Protein exit from endoplasmic reticulum →	+0.056	+0.125	<.001	<.001	3	16
STAD	Regulation of small GTPase mediated signal transduction →	+0.046	+0.136	<.001	<.001	3	16
STAD	Protein deglycosylation →	+0.058	+0.150	<.001	<.001	3	15
STAD	Phosphatidylinositol biosynthetic process →	+0.048	+0.153	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,693 associations by consensus.

Vesicle coating by IGHVIII-76-1 expression — STAD

Explore this box plot interactively →