IGHVIII-13-1

Across TCGA patient cohorts, IGHVIII-13-1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,922 significant associations in total. STAD shows the largest number of these associations.

The most reproducible IGHVIII-13-1-associated GO terms across cancer lineages are Regulation of lymphocyte apoptotic process, Immunological synapse formation, and B cell mediated immunity. Each is linked with IGHVIII-13-1 in more than 16 cancer types. Because this analysis shows association rather than direction, both IGHVIII-13-1-to-partner and partner-to-IGHVIII-13-1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of lymphocyte apoptotic process grouped by IGHVIII-13-1-low versus IGHVIII-13-1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHVIII-13-1→partner) and Y-score (partner→IGHVIII-13-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of lymphocyte apoptotic process →	+0.083	+0.080	<.001	<.001	3	17
SKCM	Immunological synapse formation →	+0.143	+0.058	<.001	<.001	3	16
THCA	B cell mediated immunity →	+0.102	+0.059	<.001	<.001	3	16
STAD	Lymphocyte activation involved in immune response →	+0.068	+0.087	<.001	<.001	3	16
STAD	B cell activation →	+0.086	+0.081	<.001	<.001	3	16
CHOL	Gamma-delta T cell activation →	+0.102	+0.128	<.001	.003	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,922 associations by consensus.

Regulation of lymphocyte apoptotic process by IGHVIII-13-1 expression — STAD

Explore this box plot interactively →