IGHVIII-13-1

Across TCGA pan-cancer cohorts, IGHVIII-13-1 RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated IGHVIII-13-1 data layer.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher IGHVIII-13-1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated IGHVIII-13-1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and BRCA show a favorable association.

STAD, KIRP, and HNSC are the cancer types where IGHVIII-13-1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	DFS	Tertile	All	0.362	0.578	<.001	96	view →
KIRP	DFS	Tertile	II,III,IV	0.151	0.702	.003	72	view →
HNSC	DFS	Tertile	III,IV	0.922	0.659	.006	72	view →
KIRC	OS	Tertile	All	0.440	0.641	<.001	60	view →
GBM	OS	Tertile	All	0.058	0.416	<.001	36	view →
BRCA	DFS	Tertile	II,III,IV	0.963	0.879	.024	36	view →
ESCA	OS	Tertile	II,III,IV	0.105	0.867	.016	27	view →
MESO	OS	Tertile	All	0.896	0.519	.023	27	view →
READ	DFS	Tertile	II,III,IV	0.190	0.805	<.001	18	view →
LUAD	DFS	Tertile	IV	0.047	0.565	<.001	18	view →
LIHC	DFS	Tertile	All	0.121	0.534	.003	18	view →
LUSC	DFS	Tertile	III,IV	0.843	0.600	.019	15	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

IGHVIII-13-1–STAD (DFS)

Open the STAD breakdown →