IGHVII-78-1

Across TCGA patient cohorts, IGHVII-78-1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,026 significant associations in total. STAD shows the largest number of these associations.

The most reproducible IGHVII-78-1-associated GO terms across cancer lineages are Peptidyl-serine autophosphorylation, Regulation of Ras protein signal transduction, and Regulation of Rho protein signal transduction. Each is linked with IGHVII-78-1 in more than 18 cancer types. Because this analysis shows association rather than direction, both IGHVII-78-1-to-partner and partner-to-IGHVII-78-1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Peptidyl-serine autophosphorylation grouped by IGHVII-78-1-low versus IGHVII-78-1-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHVII-78-1→partner) and Y-score (partner→IGHVII-78-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Peptidyl-serine autophosphorylation →	+0.063	+0.709	<.001	<.001	3	19
STAD	Regulation of Ras protein signal transduction →	+0.035	+0.431	<.001	<.001	3	18
LAML	Regulation of Rho protein signal transduction →	+0.037	+0.991	<.001	<.001	2	18
ESCA	Glycerophospholipid metabolic process →	+0.036	+0.893	<.001	<.001	3	17
STAD	Post-Golgi vesicle-mediated transport →	+0.043	+0.351	<.001	<.001	3	17
STAD	Regulation of cell morphogenesis →	+0.031	+0.354	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,026 associations by consensus.

Peptidyl-serine autophosphorylation by IGHVII-78-1 expression — ESCA

Explore this box plot interactively →