IGHVII-49-1

Across TCGA patient cohorts, IGHVII-49-1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,712 significant associations in total. STAD shows the largest number of these associations.

The most reproducible IGHVII-49-1-associated GO terms across cancer lineages are Immunoglobulin production, B cell mediated immunity, and Protein N-linked glycosylation via asparagine. Each is linked with IGHVII-49-1 in more than 9 cancer types. Because this analysis shows association rather than direction, both IGHVII-49-1-to-partner and partner-to-IGHVII-49-1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Immunoglobulin production grouped by IGHVII-49-1-low versus IGHVII-49-1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHVII-49-1→partner) and Y-score (partner→IGHVII-49-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Immunoglobulin production →	+0.081	+0.178	<.001	<.001	3	10
ESCA	B cell mediated immunity →	+0.087	+0.088	<.001	.008	2	10
STAD	Protein N-linked glycosylation via asparagine →	+0.079	+0.176	<.001	<.001	3	8
STAD	T cell activation involved in immune response →	+0.054	+0.120	<.001	<.001	3	8
ESCA	Regulation of leukocyte mediated immunity →	+0.053	+0.096	<.001	.004	2	9
STAD	Platelet activation →	+0.046	+0.123	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,712 associations by consensus.

Immunoglobulin production by IGHVII-49-1 expression — STAD

Explore this box plot interactively →