IGHVII-49-1

Across TCGA pan-cancer cohorts, IGHVII-49-1 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of IGHVII-49-1’s most consistent transcriptional readouts.

The strongest signal is observed in stomach adenocarcinoma (STAD), where IGHVII-49-1 RNA is repressed in tumor relative to normal tissue. In most cancer types IGHVII-49-1 is over-expressed in tumor, although a few such as STAD show the opposite, repressed pattern.

STAD are the cancer types where IGHVII-49-1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in IGHVII-49-1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
STAD	Female	III,IV	−0.870	.003	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 1 strongest of 1 lineages.

IGHVII-49-1–STAD

Open the STAD breakdown →