IGHVII-40-1

Across TCGA patient cohorts, IGHVII-40-1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,944 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible IGHVII-40-1-associated GO terms across cancer lineages are Mitotic cytokinesis, Positive regulation of DNA recombination, and Telomere maintenance via telomere lengthening. Each is linked with IGHVII-40-1 in more than 10 cancer types. Because this analysis shows association rather than direction, both IGHVII-40-1-to-partner and partner-to-IGHVII-40-1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic cytokinesis grouped by IGHVII-40-1-low versus IGHVII-40-1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHVII-40-1→partner) and Y-score (partner→IGHVII-40-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Mitotic cytokinesis →	+0.081	+0.183	<.001	<.001	3	11
STAD	Positive regulation of DNA recombination →	+0.067	+0.172	<.001	<.001	3	10
STAD	Telomere maintenance via telomere lengthening →	+0.075	+0.197	<.001	<.001	3	9
STAD	Mitotic nuclear division →	+0.074	+0.172	<.001	<.001	3	9
STAD	Regulation of cell cycle checkpoint →	+0.068	+0.171	<.001	<.001	3	9
STAD	Positive regulation of cell cycle checkpoint →	+0.065	+0.212	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,944 associations by consensus.

Mitotic cytokinesis by IGHVII-40-1 expression — STAD

Explore this box plot interactively →