Q-omics provides the consensus-scored IGHVII-28-1 profile across patient tissues and cancer cell-line models. IGHVII-28-1 expression is associated with patient survival in 13 of 34 cancer types, with the highest sampling consensus in THCA. Additionally, IGHVII-28-1 RNA expression shows 9,117 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight THCA, and THYM as cancer lineages where IGHVII-28-1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes IGHVII-28-1 survival associations across molecular data types. IGHVII-28-1 RNA expression shows survival associations in the most cancer types (13). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

IGHVII-28-1 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	13	THCA (135)	view →

This table ranks reproducible IGHVII-28-1 RNA expression–survival associations across cancer types. High IGHVII-28-1 expression shows unfavorable associations in THCA, READ, KIRP, KIRC and ACC, but favorable associations in LUAD. The THCA Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify THCA as the clearest survival context for IGHVII-28-1 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	DFS	Tertile	All	0.650	0.902	<.001	135	view →
LUAD	DFS	Tertile	II,III,IV	0.835	0.526	.012	57	view →
READ	OS	Tertile	All	0.364	0.927	<.001	54	view →
KIRP	DFS	Tertile	All	0.647	0.893	.012	36	view →
KIRC	DFS	Tertile	IV	0.127	0.619	.008	36	view →
ACC	OS	Tertile	All	0.118	0.624	.038	18	view →

Pink = unfavorable, green = favorable. all 13 lineages →

IGHVII-28-1-THCA (DFS)

Kaplan–Meier survival curve for IGHVII-28-1 RNA expression in THCA: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with IGHVII-28-1 in patient tissues and cancer cell lines. In patient samples, IGHVII-28-1 shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
RNA	9,117	THYM (3814)	view →
Function (RNA)	4,784	LUSC (1802)	view →