IGHVII-1-1

Across TCGA patient cohorts, IGHVII-1-1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,961 significant associations in total. STAD shows the largest number of these associations.

The most reproducible IGHVII-1-1-associated GO terms across cancer lineages are Regulation of double-strand break repair, Regulation of DNA repair, and Neural precursor cell proliferation. Each is linked with IGHVII-1-1 in more than 6 cancer types. Because this analysis shows association rather than direction, both IGHVII-1-1-to-partner and partner-to-IGHVII-1-1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of double-strand break repair grouped by IGHVII-1-1-low versus IGHVII-1-1-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHVII-1-1→partner) and Y-score (partner→IGHVII-1-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Regulation of double-strand break repair →	+0.150	+0.068	<.001	.001	3	6
ESCA	Regulation of DNA repair →	+0.164	+0.068	<.001	.002	3	6
STAD	Neural precursor cell proliferation →	+0.066	+0.084	<.001	<.001	3	6
STAD	Polysaccharide biosynthetic process →	+0.079	+0.087	<.001	<.001	3	5
STAD	Regulation of DNA-templated DNA replication →	+0.100	+0.076	<.001	<.001	3	5
STAD	Lymphocyte apoptotic process →	+0.109	+0.107	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,961 associations by consensus.

Regulation of double-strand break repair by IGHVII-1-1 expression — ESCA

Explore this box plot interactively →