Q-omics provides the consensus-scored IGHVII-1-1 profile across patient tissues and cancer cell-line models. IGHVII-1-1 expression is associated with patient survival in 10 of 34 cancer types, with the highest sampling consensus in BLCA. Additionally, IGHVII-1-1 RNA expression shows 7,518 significant gene co-expression associations, with the highest sampling consensus in COAD. Together, these results highlight BLCA, and COAD as cancer lineages where IGHVII-1-1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes IGHVII-1-1 survival associations across molecular data types. IGHVII-1-1 RNA expression shows survival associations in the most cancer types (10). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

IGHVII-1-1 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	10	BLCA (72)	view →

This table ranks reproducible IGHVII-1-1 RNA expression–survival associations across cancer types. High IGHVII-1-1 expression shows unfavorable associations in BLCA, KIRC, SKCM, LIHC, SARC and GBM. The BLCA Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify BLCA as the clearest survival context for IGHVII-1-1 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	DFS	Tertile	All	0.101	0.627	<.001	72	view →
KIRC	DFS	Tertile	All	0.488	0.807	<.001	48	view →
SKCM	OS	Tertile	All	0.305	0.785	<.001	36	view →
LIHC	OS	Tertile	All	0.331	0.690	.011	30	view →
SARC	OS	Tertile	All	0.022	0.861	<.001	27	view →
GBM	DFS	Tertile	All	0.066	0.257	.019	18	view →

Pink = unfavorable, green = favorable. all 10 lineages →

IGHVII-1-1-BLCA (DFS)

Kaplan–Meier survival curve for IGHVII-1-1 RNA expression in BLCA: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with IGHVII-1-1 in patient tissues and cancer cell lines. In patient samples, IGHVII-1-1 shows the broadest associations at the RNA and protein expression levels, with COAD recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
RNA	7,518	COAD (4585)	view →
Function (RNA)	5,961	STAD (5657)	view →