IGHV4OR15-8

Across TCGA patient cohorts, IGHV4OR15-8 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,368 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IGHV4OR15-8-associated proteins across cancer lineages are CD38, IGHG1, and IL16. Each is linked with IGHV4OR15-8 in more than 6 cancer types. Because this analysis shows association rather than direction, both IGHV4OR15-8-to-partner and partner-to-IGHV4OR15-8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IGHV4OR15-8 versus CD38 in OV, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHV4OR15-8→partner) and Y-score (partner→IGHV4OR15-8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CD38 →	+0.955	+0.216	<.001	<.001	3	7
OV	IGHG1 →	+0.639	+0.185	.004	.004	3	7
BRCA	IL16 →	+0.539	+0.466	<.001	<.001	3	7
OV	MZB1 →	+1.757	+0.216	<.001	<.001	3	7
UCEC	ADA2 →	+0.588	+0.147	<.001	.001	3	6
LSCC	CSDE1_S514 →	+0.862	+0.712	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,368 associations by consensus.

IGHV4OR15-8 vs CD38 — OV

Explore this scatter interactively →