IGHV4OR15-8

Across TCGA patient cohorts, IGHV4OR15-8 protein abundance is significantly associated with the RNA expression of many other genes, with 161 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible IGHV4OR15-8-associated genes across cancer lineages are GML, ETFB, and KCNJ2. Each is linked with IGHV4OR15-8 in more than 1 cancer types. Because this analysis shows association rather than direction, both IGHV4OR15-8-to-partner and partner-to-IGHV4OR15-8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IGHV4OR15-8 versus GML in LUAD, with a Pearson correlation of -0.52.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHV4OR15-8→partner) and Y-score (partner→IGHV4OR15-8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	GML →	-0.198	-0.585	.003	.003	3	1
LUAD	ETFB →	-0.535	-0.607	.003	.003	3	1
LUAD	KCNJ2 →	+0.942	+0.687	.002	.001	3	1
LUAD	FHOD1 →	-0.736	-0.717	.002	.002	3	1
LUAD	HIGD2A →	-0.438	-0.713	.004	.001	3	1
LUAD	PPP4R1 →	-0.436	-0.599	.004	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 161 associations by consensus.

IGHV4OR15-8 vs GML — LUAD

Explore this scatter interactively →