IGHV3OR16-8

Across TCGA patient cohorts, IGHV3OR16-8 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,567 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IGHV3OR16-8-associated proteins across cancer lineages are IRF4, MZB1, and CD38. Each is linked with IGHV3OR16-8 in more than 8 cancer types. Because this analysis shows association rather than direction, both IGHV3OR16-8-to-partner and partner-to-IGHV3OR16-8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IGHV3OR16-8 versus IRF4 in LSCC, with a Pearson correlation of 0.81.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHV3OR16-8→partner) and Y-score (partner→IGHV3OR16-8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	IRF4 →	+1.027	+1.720	<.001	<.001	3	9
OV	MZB1 →	+1.593	+0.413	<.001	<.001	3	9
OV	CD38 →	+0.936	+0.391	<.001	<.001	3	9
OV	RASAL3 →	+0.447	+0.519	<.001	<.001	3	8
BRCA	SEPTIN1 →	+0.643	+0.451	<.001	<.001	3	8
GBM	LPXN →	+0.583	+0.102	.001	.007	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,567 associations by consensus.

IGHV3OR16-8 vs IRF4 — LSCC

Explore this scatter interactively →