IGHV3OR16-8

Across TCGA patient cohorts, IGHV3OR16-8 protein abundance is significantly associated with the RNA expression of many other genes, with 511 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible IGHV3OR16-8-associated genes across cancer lineages are IL36B, SLC24A4, and PKD1L2. Each is linked with IGHV3OR16-8 in more than 1 cancer types. Because this analysis shows association rather than direction, both IGHV3OR16-8-to-partner and partner-to-IGHV3OR16-8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IGHV3OR16-8 versus IL36B in LUAD, with a Pearson correlation of 0.78.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHV3OR16-8→partner) and Y-score (partner→IGHV3OR16-8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	IL36B →	+0.298	+2.138	<.001	<.001	3	1
LUAD	SLC24A4 →	-0.269	-1.600	.007	.005	3	1
LUAD	PKD1L2 →	-0.764	-1.398	<.001	.004	3	1
LUAD	RNU4-31P →	-0.868	-1.374	<.001	.005	3	1
LUAD	CDK7P1 →	+0.222	+1.427	.001	.003	3	1
LUAD	MIR548N →	-1.092	-1.344	.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 511 associations by consensus.

IGHV3OR16-8 vs IL36B — LUAD

Explore this scatter interactively →