IGHV3OR16-7

Across TCGA patient cohorts, IGHV3OR16-7 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,843 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible IGHV3OR16-7-associated GO terms across cancer lineages are B cell receptor signaling pathway, B cell mediated immunity, and Positive regulation of B cell activation. Each is linked with IGHV3OR16-7 in more than 26 cancer types. Because this analysis shows association rather than direction, both IGHV3OR16-7-to-partner and partner-to-IGHV3OR16-7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, B cell receptor signaling pathway grouped by IGHV3OR16-7-low versus IGHV3OR16-7-high in CHOL.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHV3OR16-7→partner) and Y-score (partner→IGHV3OR16-7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CHOL	B cell receptor signaling pathway →	+0.103	+0.211	<.001	<.001	3	27
THCA	B cell mediated immunity →	+0.108	+0.429	<.001	<.001	3	27
CHOL	Positive regulation of B cell activation →	+0.047	+0.198	<.001	.002	3	26
THCA	Antibacterial humoral response →	+0.171	+0.395	<.001	<.001	3	26
STAD	Immunoglobulin production →	+0.087	+0.908	<.001	<.001	3	26
CHOL	Antigen receptor-mediated signaling pathway →	+0.071	+0.272	<.001	<.001	3	25

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,843 associations by consensus.

B cell receptor signaling pathway by IGHV3OR16-7 expression — CHOL

Explore this box plot interactively →