IGHV3OR16-17

Across TCGA patient cohorts, IGHV3OR16-17 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,855 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IGHV3OR16-17-associated proteins across cancer lineages are MZB1, SEPTIN6, and CD38. Each is linked with IGHV3OR16-17 in more than 8 cancer types. Because this analysis shows association rather than direction, both IGHV3OR16-17-to-partner and partner-to-IGHV3OR16-17 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IGHV3OR16-17 versus MZB1 in GBM, with a Pearson correlation of 0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHV3OR16-17→partner) and Y-score (partner→IGHV3OR16-17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MZB1 →	+1.413	+0.120	<.001	.002	3	9
LSCC	SEPTIN6 →	+0.352	+1.443	<.001	<.001	3	7
BRCA	CD38 →	+0.823	+0.335	<.001	<.001	3	7
LSCC	IRF4 →	+0.918	+1.696	<.001	<.001	3	7
GBM	TRAF3IP3 →	+0.558	+0.086	.008	.006	2	7
BRCA	PRKCB →	+0.548	+0.556	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,855 associations by consensus.

IGHV3OR16-17 vs MZB1 — GBM

Explore this scatter interactively →