IGHV3OR16-10

Across TCGA patient cohorts, IGHV3OR16-10 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,016 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible IGHV3OR16-10-associated GO terms across cancer lineages are Antibacterial humoral response, Complement activation, and B cell receptor signaling pathway. Each is linked with IGHV3OR16-10 in more than 29 cancer types. Because this analysis shows association rather than direction, both IGHV3OR16-10-to-partner and partner-to-IGHV3OR16-10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Antibacterial humoral response grouped by IGHV3OR16-10-low versus IGHV3OR16-10-high in THCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHV3OR16-10→partner) and Y-score (partner→IGHV3OR16-10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THCA	Antibacterial humoral response →	+0.168	+1.013	<.001	<.001	3	30
THCA	Complement activation →	+0.149	+0.932	<.001	<.001	3	29
CHOL	B cell receptor signaling pathway →	+0.101	+1.320	<.001	.001	3	28
CHOL	B cell mediated immunity →	+0.112	+1.826	<.001	<.001	3	28
SARC	Antimicrobial humoral response →	+0.116	+0.322	<.001	<.001	3	28
THCA	Humoral immune response mediated by circulating immunoglobulin →	+0.159	+0.941	<.001	<.001	3	28

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,016 associations by consensus.

Antibacterial humoral response by IGHV3OR16-10 expression — THCA

Explore this box plot interactively →