IGHV3OR16-10

Across TCGA patient cohorts, IGHV3OR16-10 protein abundance is significantly associated with the RNA expression of many other genes, with 3,467 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible IGHV3OR16-10-associated genes across cancer lineages are ALOX5AP, IGHV3-41, and DLGAP1. Each is linked with IGHV3OR16-10 in more than 2 cancer types. Because this analysis shows association rather than direction, both IGHV3OR16-10-to-partner and partner-to-IGHV3OR16-10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IGHV3OR16-10 versus ALOX5AP in HNSC, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHV3OR16-10→partner) and Y-score (partner→IGHV3OR16-10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ALOX5AP →	+0.961	+0.956	<.001	.002	3	3
LUAD	IGHV3-41 →	+0.605	+0.770	.001	.001	3	3
OV	DLGAP1 →	+0.840	+1.202	.006	.006	3	2
OV	YJEFN3 →	-1.219	-1.522	.009	.002	3	2
HNSC	NCF4 →	+1.173	+1.139	<.001	<.001	3	2
HNSC	CSF2RB →	+1.075	+1.001	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,467 associations by consensus.

IGHV3OR16-10 vs ALOX5AP — HNSC

Explore this scatter interactively →