IGHV3-79

Across TCGA patient cohorts, IGHV3-79 RNA expression is significantly associated with the RNA expression of many other genes, with 12,658 significant associations in total. ESCA shows the largest number of these associations.

The most reproducible IGHV3-79-associated genes across cancer lineages are IGHV7-81, IGHV5-78, and IGHV3-74. Each is linked with IGHV3-79 in more than 30 cancer types. Because this analysis shows association rather than direction, both IGHV3-79-to-partner and partner-to-IGHV3-79 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IGHV3-79 versus IGHV7-81 in LUSC, with a Pearson correlation of 0.64.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHV3-79→partner) and Y-score (partner→IGHV3-79) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	IGHV7-81 →	+1.695	+0.803	<.001	<.001	3	31
LUSC	IGHV5-78 →	+1.790	+0.758	<.001	<.001	3	28
THCA	IGHV3-74 →	+4.197	+0.573	<.001	<.001	3	27
LAML	IGHVII-78-1 →	+1.203	+1.307	<.001	<.001	3	27
THCA	IGHJ1 →	+2.830	+0.585	<.001	<.001	3	26
THCA	IGHV2-5 →	+3.142	+0.569	<.001	<.001	3	26

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,658 associations by consensus.

IGHV3-79 vs IGHV7-81 — LUSC

Explore this scatter interactively →