IGHV3-79

Across TCGA patient cohorts, IGHV3-79 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,792 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible IGHV3-79-associated proteins across cancer lineages are ACSL5, NCOA2_S699, and ARHGEF38_S55. Each is linked with IGHV3-79 in more than 4 cancer types. Because this analysis shows association rather than direction, both IGHV3-79-to-partner and partner-to-IGHV3-79 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IGHV3-79 versus ACSL5 in UCEC, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHV3-79→partner) and Y-score (partner→IGHV3-79) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ACSL5 →	+1.231	+1.323	<.001	<.001	3	5
PDAC	NCOA2_S699 →	+0.350	+1.226	<.001	<.001	3	3
OV	ARHGEF38_S55 →	+1.560	+0.336	<.001	.002	3	3
UCEC	ST13_S79 →	-0.594	-1.209	<.001	<.001	3	3
LSCC	TRA2B_T201 →	-0.812	-0.587	<.001	<.001	3	3
PDAC	SLC2A3_S485 →	-0.723	-0.775	.006	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,792 associations by consensus.

IGHV3-79 vs ACSL5 — UCEC

Explore this scatter interactively →