Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts
Across TCGA patient cohorts, IGHV3-66 mutation is significantly associated with the RNA expression of many other genes, with 109 significant associations in total. BRCA shows the largest number of these associations.
The most reproducible IGHV3-66-associated genes across cancer lineages are MTND6P16, RNA5SP287, and RNA5SP404. Each is linked with IGHV3-66 in more than 1 cancer types. Because this analysis shows association rather than direction, both IGHV3-66-to-partner and partner-to-IGHV3-66 results are reported.
Each partner links to its own Q-omics profile.
mutation associated genes by consensus
Ranked by combined sampling and lineage consensus. X-score (IGHV3-66→partner) and Y-score (partner→IGHV3-66) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.