IGHV1OR15-1

Across TCGA patient cohorts, IGHV1OR15-1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,446 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible IGHV1OR15-1-associated GO terms across cancer lineages are B cell mediated immunity, Immunoglobulin production, and Positive regulation of leukocyte proliferation. Each is linked with IGHV1OR15-1 in more than 24 cancer types. Because this analysis shows association rather than direction, both IGHV1OR15-1-to-partner and partner-to-IGHV1OR15-1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, B cell mediated immunity grouped by IGHV1OR15-1-low versus IGHV1OR15-1-high in THCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHV1OR15-1→partner) and Y-score (partner→IGHV1OR15-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THCA	B cell mediated immunity →	+0.115	+0.313	<.001	<.001	3	25
THCA	Immunoglobulin production →	+0.081	+0.309	<.001	<.001	3	25
SKCM	Positive regulation of leukocyte proliferation →	+0.055	+0.238	<.001	<.001	3	24
DLBC	Dendritic cell apoptotic process →	+0.097	+0.138	<.001	<.001	3	24
THCA	Antibacterial humoral response →	+0.182	+0.289	<.001	<.001	3	24
SKCM	Regulation of leukocyte proliferation →	+0.050	+0.228	<.001	<.001	3	23

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,446 associations by consensus.

B cell mediated immunity by IGHV1OR15-1 expression — THCA

Explore this box plot interactively →