IGHV1-24

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, IGHV1-24 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IGHV1-24-associated genes across cancer lineages are Th2 cells and Hepatocytes. Each is linked with IGHV1-24 in more than 1 cancer types. Because this analysis shows association rather than direction, both IGHV1-24-to-partner and partner-to-IGHV1-24 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHV1-24→partner) and Y-score (partner→IGHV1-24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECTh2 cells →+0.207+3.000.047.03731
SKCMHepatocytes →-0.014-2.315.048.03621
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

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