IGFBPL1

Across TCGA patient cohorts, IGFBPL1 protein abundance is significantly associated with the RNA expression of many other genes, with 2,422 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IGFBPL1-associated genes across cancer lineages are GID8, ANKRD27, and ENO3. Each is linked with IGFBPL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both IGFBPL1-to-partner and partner-to-IGFBPL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IGFBPL1 versus GID8 in LUAD, with a Pearson correlation of 0.69.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGFBPL1→partner) and Y-score (partner→IGFBPL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	GID8 →	+0.801	+2.345	<.001	.002	3	2
LSCC	ANKRD27 →	+0.735	+0.975	.001	.002	3	2
LUAD	ENO3 →	+1.968	+2.201	.006	.004	3	2
LSCC	GLRB →	+0.875	+0.993	.005	.004	3	2
LSCC	ERI3 →	+0.790	+1.299	<.001	<.001	3	2
LSCC	PIGT →	+0.681	+1.355	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,422 associations by consensus.

IGFBPL1 vs GID8 — LUAD

Explore this scatter interactively →