IGFALS

Across TCGA patient cohorts, IGFALS protein abundance is significantly associated with the RNA expression of many other genes, with 14,403 significant associations in total. GBM shows the largest number of these associations.

The most reproducible IGFALS-associated genes across cancer lineages are LINC00702, FLT1, and PCOLCE. Each is linked with IGFALS in more than 8 cancer types. Because this analysis shows association rather than direction, both IGFALS-to-partner and partner-to-IGFALS results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IGFALS versus LINC00702 in HNSC, with a Pearson correlation of 0.30.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGFALS→partner) and Y-score (partner→IGFALS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	LINC00702 →	+0.613	+0.410	.001	.001	3	9
OV	FLT1 →	+0.856	+0.712	.001	<.001	3	8
OV	PCOLCE →	+1.257	+0.665	<.001	<.001	3	8
COAD	SERPINE1 →	+1.444	+0.431	<.001	<.001	3	8
COAD	FN1 →	+2.154	+0.604	<.001	<.001	3	8
GBM	MMP19 →	+1.380	+0.692	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,403 associations by consensus.

IGFALS vs LINC00702 — HNSC

Explore this scatter interactively →