IGF2BP3

Across TCGA patient cohorts, IGF2BP3 protein abundance is significantly associated with the RNA expression of many other genes, with 15,098 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IGF2BP3-associated genes across cancer lineages are SNORD65C, CDCA3, and HJURP. Each is linked with IGF2BP3 in more than 8 cancer types. Because this analysis shows association rather than direction, both IGF2BP3-to-partner and partner-to-IGF2BP3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IGF2BP3 versus SNORD65C in HNSC, with a Pearson correlation of 0.75.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGF2BP3→partner) and Y-score (partner→IGF2BP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SNORD65C →	+2.867	+1.838	<.001	<.001	3	9
PDAC	CDCA3 →	+0.725	+1.075	<.001	<.001	3	8
UCEC	HJURP →	+1.185	+1.798	<.001	<.001	3	8
HNSC	RNU7-143P →	+2.510	+1.876	<.001	<.001	3	8
GBM	PIMREG →	+1.005	+0.779	<.001	<.001	3	7
UCEC	TOP2A →	+1.411	+2.015	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,098 associations by consensus.

IGF2BP3 vs SNORD65C — HNSC

Explore this scatter interactively →