IGF2BP1

Across TCGA patient cohorts, IGF2BP1 protein abundance is significantly associated with the RNA expression of many other genes, with 7,867 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IGF2BP1-associated genes across cancer lineages are RNU6-826P, POTEE, and RAB38. Each is linked with IGF2BP1 in more than 4 cancer types. Because this analysis shows association rather than direction, both IGF2BP1-to-partner and partner-to-IGF2BP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IGF2BP1 versus RNU6-826P in HNSC, with a Pearson correlation of 0.68.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGF2BP1→partner) and Y-score (partner→IGF2BP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RNU6-826P →	+1.089	+1.906	<.001	<.001	3	5
LSCC	POTEE →	+1.709	+1.321	<.001	<.001	3	4
LSCC	RAB38 →	-0.979	-1.490	.002	.002	2	4
UCEC	INTS12 →	-0.399	-1.560	.003	.008	3	3
UCEC	CCDC173 →	-1.216	-1.963	<.001	<.001	3	3
UCEC	UBXN10 →	-1.776	-2.213	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,867 associations by consensus.

IGF2BP1 vs RNU6-826P — HNSC

Explore this scatter interactively →