IGF2-AS

Across TCGA patient cohorts, IGF2-AS RNA expression is significantly associated with the go_rna of many other GO terms, with 6,916 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible IGF2-AS-associated GO terms across cancer lineages are Regulation of glycogen (starch) synthase activity, Exocrine pancreas development, and Regulation of skeletal muscle tissue growth. Each is linked with IGF2-AS in more than 24 cancer types. Because this analysis shows association rather than direction, both IGF2-AS-to-partner and partner-to-IGF2-AS results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of glycogen (starch) synthase activity grouped by IGF2-AS-low versus IGF2-AS-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGF2-AS→partner) and Y-score (partner→IGF2-AS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Regulation of glycogen (starch) synthase activity →	+0.083	+0.216	<.001	<.001	3	25
TGCT	Exocrine pancreas development →	+0.167	+0.755	<.001	<.001	3	24
UCS	Regulation of skeletal muscle tissue growth →	+0.116	+3.696	<.001	<.001	2	23
ESCA	Positive regulation of skeletal muscle tissue growth →	+0.087	+0.126	<.001	<.001	2	23
TGCT	Mesenchymal cell differentiation →	+0.062	+0.745	<.001	<.001	3	21
TGCT	Cardiac epithelial to mesenchymal transition →	+0.088	+0.667	<.001	<.001	3	21

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,916 associations by consensus.

Regulation of glycogen (starch) synthase activity by IGF2-AS expression — ESCA

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