IGF2-AS

Across TCGA patient cohorts, IGF2-AS protein abundance is significantly associated with the RNA expression of many other genes, with 6,296 significant associations in total. GBM shows the largest number of these associations.

The most reproducible IGF2-AS-associated genes across cancer lineages are SPINT5P, TIMP1, and HOXA5. Each is linked with IGF2-AS in more than 2 cancer types. Because this analysis shows association rather than direction, both IGF2-AS-to-partner and partner-to-IGF2-AS results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IGF2-AS versus SPINT5P in LUAD, with a Pearson correlation of -0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGF2-AS→partner) and Y-score (partner→IGF2-AS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	SPINT5P →	-1.405	-0.829	.001	.003	3	3
OV	TIMP1 →	-0.987	-0.972	.001	.001	3	2
OV	HOXA5 →	-1.396	-0.925	<.001	.002	3	2
OV	ACTA2 →	-2.259	-1.405	<.001	<.001	3	2
GBM	ASPA →	-0.737	-0.411	.008	.005	3	2
CCRCC	ABCC3 →	-0.666	-0.248	.003	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,296 associations by consensus.

IGF2-AS vs SPINT5P — LUAD

Explore this scatter interactively →