IFT80

Across TCGA patient cohorts, IFT80 protein abundance is significantly associated with the RNA expression of many other genes, with 5,999 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible IFT80-associated genes across cancer lineages are SPAG8, SPEF1, and CCDC113. Each is linked with IFT80 in more than 3 cancer types. Because this analysis shows association rather than direction, both IFT80-to-partner and partner-to-IFT80 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IFT80 versus SPAG8 in UCEC, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IFT80→partner) and Y-score (partner→IFT80) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SPAG8 →	+1.131	+0.384	<.001	.002	3	4
UCEC	SPEF1 →	+1.492	+0.422	<.001	.001	3	4
UCEC	CCDC113 →	+0.772	+0.349	<.001	.001	3	4
UCEC	RSPH4A →	+1.351	+0.419	<.001	.001	3	4
BRCA	OSCP1 →	+0.685	+0.224	<.001	<.001	3	4
BRCA	CFAP94 →	+0.939	+0.267	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,999 associations by consensus.

IFT80 vs SPAG8 — UCEC

Explore this scatter interactively →