IFT74

Across TCGA patient cohorts, IFT74 protein abundance is significantly associated with the RNA expression of many other genes, with 12,439 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible IFT74-associated genes across cancer lineages are DNAH7, PIH1D2, and RIBC1. Each is linked with IFT74 in more than 8 cancer types. Because this analysis shows association rather than direction, both IFT74-to-partner and partner-to-IFT74 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IFT74 versus DNAH7 in UCEC, with a Pearson correlation of 0.62.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IFT74→partner) and Y-score (partner→IFT74) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	DNAH7 →	+1.135	+0.360	<.001	<.001	3	9
BRCA	PIH1D2 →	+0.867	+0.391	<.001	<.001	3	8
UCEC	RIBC1 →	+1.140	+0.339	<.001	<.001	3	8
GBM	CFAP91 →	+1.035	+0.345	<.001	.001	3	8
UCEC	SPEF1 →	+1.749	+0.326	<.001	<.001	3	7
BRCA	CFAP69 →	+1.138	+0.397	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,439 associations by consensus.

IFT74 vs DNAH7 — UCEC

Explore this scatter interactively →