IFT122

Across TCGA patient cohorts, IFT122 protein abundance is significantly associated with the RNA expression of many other genes, with 12,598 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible IFT122-associated genes across cancer lineages are DNAH7, DRC3, and SPEF1. Each is linked with IFT122 in more than 7 cancer types. Because this analysis shows association rather than direction, both IFT122-to-partner and partner-to-IFT122 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IFT122 versus DNAH7 in UCEC, with a Pearson correlation of 0.57.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IFT122→partner) and Y-score (partner→IFT122) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	DNAH7 →	+1.113	+0.417	<.001	<.001	3	8
BRCA	DRC3 →	+1.402	+0.447	<.001	<.001	3	8
UCEC	SPEF1 →	+1.575	+0.259	<.001	<.001	3	7
OV	CFAP94 →	+1.436	+0.324	<.001	.003	3	7
UCEC	SPAG8 →	+1.593	+0.374	<.001	<.001	3	7
BRCA	PIH1D2 →	+0.920	+0.369	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,598 associations by consensus.

IFT122 vs DNAH7 — UCEC

Explore this scatter interactively →