IFNK

Across TCGA patient cohorts, IFNK RNA expression is significantly associated with the protein abundance of many other proteins, with 8,614 significant associations in total. GBM shows the largest number of these associations.

The most reproducible IFNK-associated proteins across cancer lineages are PLAA, UBA7, and SAMHD1. Each is linked with IFNK in more than 3 cancer types. Because this analysis shows association rather than direction, both IFNK-to-partner and partner-to-IFNK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IFNK versus PLAA in LSCC, with a Pearson correlation of 0.49.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IFNK→partner) and Y-score (partner→IFNK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PLAA →	+0.440	+0.778	<.001	<.001	3	4
HNSC	UBA7 →	+0.390	+0.737	<.001	<.001	3	4
HNSC	SAMHD1 →	+0.543	+0.877	<.001	.001	3	4
GBM	CCDC88B_S1379 →	+0.501	+0.722	.001	.002	3	4
LUAD	DHODH →	-0.344	-0.459	<.001	.001	3	4
GBM	AIF1 →	+0.519	+0.614	.001	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,614 associations by consensus.

IFNK vs PLAA — LSCC

Explore this scatter interactively →