IFNK

Across TCGA patient cohorts, IFNK mutation is significantly associated with the RNA expression of many other genes, with 19 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IFNK-associated genes across cancer lineages are LINC02394, MIR5704, and MIR4440. Each is linked with IFNK in more than 1 cancer types. Because this analysis shows association rather than direction, both IFNK-to-partner and partner-to-IFNK results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02394 grouped by IFNK-low versus IFNK-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IFNK→partner) and Y-score (partner→IFNK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	LINC02394 →	+0.142	+5.411	<.001	.005	3	1
BLCA	MIR5704 →	+0.736	+6.289	<.001	.001	3	1
BLCA	MIR4440 →	+0.573	+5.899	<.001	.002	3	1
BLCA	CEACAMP7 →	+0.164	+5.106	<.001	.008	3	1
UCEC	RNU1-17P →	+0.369	+3.520	<.001	.006	3	1
UCEC	RNU6-701P →	+0.378	+3.386	.004	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

LINC02394 by IFNK expression — BLCA

Explore this box plot interactively →