IFNA8

Across TCGA patient cohorts, IFNA8 mutation is significantly associated with the RNA expression of many other genes, with 976 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IFNA8-associated genes across cancer lineages are OR10H2, RNU6-947P, and DSCR4. Each is linked with IFNA8 in more than 1 cancer types. Because this analysis shows association rather than direction, both IFNA8-to-partner and partner-to-IFNA8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10H2 grouped by IFNA8-low versus IFNA8-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IFNA8→partner) and Y-score (partner→IFNA8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	OR10H2 →	+0.041	+4.690	.002	.003	3	2
STAD	RNU6-947P →	+0.327	+5.026	<.001	.009	3	2
LUAD	DSCR4 →	+0.603	+3.468	.004	.005	3	2
LUAD	RNA5SP139 →	+0.667	+3.875	<.001	.004	3	2
LUAD	RNU6-158P →	+0.442	+3.745	<.001	.005	3	2
LUAD	RNU6-1028P →	+0.214	+4.584	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 976 associations by consensus.

OR10H2 by IFNA8 expression — LIHC

Explore this box plot interactively →