IFNA4

Across TCGA cell cohorts, IFNA4 RNA expression is significantly associated with the mutation status of many other genes, with 162 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible IFNA4-associated genes across cancer lineages are SPATA17, FAM189B, and PTCHD3. Each is linked with IFNA4 in more than 1 cancer types. Because this analysis shows association rather than direction, both IFNA4-to-partner and partner-to-IFNA4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SPATA17 grouped by IFNA4-low versus IFNA4-high in LUNG_NSCLC_LUSC.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IFNA4→partner) and Y-score (partner→IFNA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	SPATA17 →	+4.584	+0.115	.001	<.001	3	2
BLOOD_Leukemia	FAM189B →	+2.922	+0.023	.009	<.001	3	2
SKIN	PTCHD3 →	+3.977	+0.026	.001	<.001	3	2
CNS	MICAL3 →	+3.321	+0.082	.003	<.001	3	2
BLOOD_Myeloma	MYO1E →	+4.807	+0.033	.006	<.001	3	1
BLOOD_Myeloma	WDR87 →	+4.807	+0.033	.006	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 162 associations by consensus.

SPATA17 by IFNA4 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →