IFNA4

Across TCGA pan-cancer cohorts, IFNA4 RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated IFNA4 data layer compared with 4 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher IFNA4 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated IFNA4 expression acts as an unfavorable survival marker.

UCEC, HNSC, and STAD are the cancer types where IFNA4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Tertile	All	0.591	0.878	<.001	108	view →
HNSC	DFS	Tertile	All	0.347	0.701	<.001	99	view →
STAD	DFS	Tertile	All	0.429	0.668	.005	72	view →
LIHC	DFS	Tertile	All	0.066	0.555	<.001	69	view →
CESC	DFS	Tertile	II,III,IV	0.144	0.705	.004	54	view →
KIRP	DFS	Tertile	All	0.142	0.613	<.001	51	view →
GBM	DFS	Tertile	All	0.083	0.244	.031	18	view →
LUAD	OS	Tertile	III,IV	0.295	0.666	.036	18	view →
LGG	DFS	Tertile	All	0.448	0.847	.003	9	view →

Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

IFNA4–UCEC (OS)

Open the UCEC breakdown →