Across TCGA patient cohorts, IFNA2 mutation is significantly associated with the RNA expression of many other genes, with 1,997 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IFNA2-associated genes across cancer lineages are MIR6731, MIR4445, and HMGB1P9. Each is linked with IFNA2 in more than 1 cancer types. Because this analysis shows association rather than direction, both IFNA2-to-partner and partner-to-IFNA2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IFNA2→partner) and Y-score (partner→IFNA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MIR6731 →	+0.851	+4.221	<.001	.003	3	2
BRCA	MIR4445 →	+0.326	+7.731	<.001	.009	3	2
UCEC	HMGB1P9 →	+0.131	+2.277	.003	.001	3	2
SKCM	RNU4-58P →	+0.242	+4.385	<.001	.008	3	2
SKCM	RNU6-932P →	+0.214	+4.495	<.001	.007	3	2
BRCA	TSPY13P →	+0.029	+9.057	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,997 associations by consensus.

Exploration

IFNA2 survival (RNA) · tumor vs normal (RNA) · all IFNA2 data types