IFNA16

Across TCGA patient cohorts, IFNA16 mutation is significantly associated with the total protein of many other genes, with 2 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible IFNA16-associated genes across cancer lineages are Acetyl-a-Tubulin-Lys40 and Src_pY416. Each is linked with IFNA16 in more than 1 cancer types. Because this analysis shows association rather than direction, both IFNA16-to-partner and partner-to-IFNA16 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Acetyl-a-Tubulin-Lys40 grouped by IFNA16-low versus IFNA16-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IFNA16→partner) and Y-score (partner→IFNA16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Acetyl-a-Tubulin-Lys40 →	+0.635	+2.321	.020	.035	3	1
SKCM	Src_pY416 →	-0.310	-2.321	.043	.035	2	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Acetyl-a-Tubulin-Lys40 by IFNA16 expression — SKCM

Explore this box plot interactively →